Transmembrane Protease, Serine 2 (TMPRSS2) Antibody
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Description
TMPRSS2 Antibody is a Goat Polyclonal antibody against TMPRSS2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transmembrane Protease, Serine 2 (TMPRSS2) |
| Host | Goat |
| Reactivity | Human |
| Recommended Dilution | P-ELISA: 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 7113 |
| NCBI Accession | NP_005647.2 |
| Background | Antibody anti-TMPRSS2 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
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TMPRSS2 antibody
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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