Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455449
tested applications
ELISA, WB, IHC
Description
Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody is a Rabbit polyclonal antibody for the detection of Human Transmembrane Emp24 Domain-Containing Protein 10 (TMED10).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Immunogen: Recombinant Transmembrane Emp24 Domain-Containing Protein 10 (Ile32-Lys133) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C for up to 2 weeks. For long-term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49755 |
| Gene ID | 10972 |
| NCBI Accession | NP_006818.3 |
| Alias | TMP21,p23,TMP21,p24d1,S31I125,Tmp-21-I,S31III125,P24(DELTA) |
| Background | Antibody anti-TMED10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
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