Transforming Growth Factor-Beta Receptor-Associated Protein 1 (TGFBRAP1) Antibody

Product Graph
377€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Transforming Growth Factor-Beta Receptor-Associated Protein 1 (TGFBRAP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx238646
tested applications
ELISA, WB, IHC, IF/ICC

Description

TGFBRAP1 Antibody is a Rabbit Polyclonal against TGFBRAP1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Transforming Growth Factor-Beta Receptor-Associated Protein 1 (TGFBRAP1)
Immunogen: transforming growth factor, beta receptor associated protein 1
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: 2 mg/ml
Recommended Dilution
WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 80 kDa
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8WUH2
Gene ID
9392
OMIM
606237
Background
Antibody anti-TGFBRAP1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

FNab08646

TGFBRAP1 antibody

Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes and in degradative but not recycling trafficking of endocytosed cargo(PubMed:25266290).

Ver Producto
P6266

Recombinant Human TGFBRAP1

Ver Producto
abx027385

Transforming Growth Factor-Beta Receptor-Associated Protein 1 (TGFBRAP1) Antibody

TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.

Ver Producto