Transcription Factor EB (TFEB) Antibody

312€ (60 µl)
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935106861
info@markelab.com
name
Transcription Factor EB (TFEB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005518
tested applications
WB, IHC, IF/ICC
Description
TFEB Antibody is a Rabbit Polyclonal antibody against TFEB.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Transcription Factor EB (TFEB) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P19484 |
Gene ID | 7942 |
NCBI Accession | NP_009093.1 |
Background | Antibody anti-TFEB |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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TFEB antibody
TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB. The calcualted molecular weight of TFEB is 53 kDa, but modified TFEB is about 65-70 kDa.
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