Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody
286€ (100 µl)
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935106861
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name
Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx178647
tested applications
WB, IHC, IF/ICC
Description
Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody is a Rabbit Polyclonal antibody against Transcription Factor Binding To IGHM Enhancer 3 (TFE3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transcription Factor Binding To IGHM Enhancer 3 (TFE3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Antibody anti-TFE3 |
| Status | RUO |
Descripción
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Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
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Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody
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