Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody

364€ (100 µg)
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935106861
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name
Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx238626
tested applications
ELISA, WB, IHC, IP
Description
TFE3 Antibody is a Rabbit Polyclonal against TFE3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transcription Factor Binding To IGHM Enhancer 3 (TFE3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/50 - 1/500, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P19532 |
| Gene ID | 7030 |
| OMIM | 314310 |
| Background | Antibody anti-TFE3 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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TFE3 antibody
Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
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Transcription Factor Binding To IGHM Enhancer 3 (TFE3) Antibody
TFE3 Antibody is a Rabbit Polyclonal Antibody against TFE3.
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