Transcription Factor Binding To Ighm Enhancer 3 (TFE3) Antibody

637€ (100 µl)
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935106861
info@markelab.com
name
Transcription Factor Binding To Ighm Enhancer 3 (TFE3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx116162
tested applications
ELISA, WB
Description
Transcription Factor Binding To Ighm Enhancer 3 Antibody is a Rabbit Polyclonal antibody against Transcription Factor Binding To Ighm Enhancer 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Transcription Factor Binding To Ighm Enhancer 3 (TFE3) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P19532 |
Gene ID | 7030 |
NCBI Accession | NP_001269071.1, NM_001282142.1, NP_006512.2, NM_006521.5 |
OMIM | 314310 |
Background | Antibody anti-TFE3 |
Status | RUO |
Descripción
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Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
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