TRAF3 Interacting Protein 2 (TRAF3IP2) Antibody

Name: TRAF3 Interacting Protein 2 (TRAF3IP2) Antibody
Brand: Abbexa
SKU: abx433396
Price: 416 EUR
Availability: OnlineOnly

Este producto es parte de TRAF3IP - TRAF3-interacting protein

Pida mas información

935106861

info@markelab.com

Precio

416€ (200 µl)

Antibody anti-TRAF3IP2

proveedor

Abbexa

reference

abx433396

Tested Applications

P-ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

TRAF3IP2 Antibody is a Goat Polyclonal antibody against TRAF3IP2.

Background

RAF3-interacting protein 2 (TRAF3IP2), also known as Act1, is an adaptor protein that plays a key role in the regulation of inflammatory and immune responses by linking receptors such as IL-17 and CD40 to downstream signaling pathways. It interacts with TRAF family proteins to activate NF-kappa-B, MAPKs, and other transcriptional regulators critical for cytokine production and immune cell activation. TRAF3IP2 is essential for IL-17-mediated signaling, contributing to pro-inflammatory responses in autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis. It also regulates B-cell survival and antibody production through interactions with CD40 and BAFF receptor pathways. Dysregulation or mutations in TRAF3IP2 are associated with increased inflammation, immune dysregulation, and susceptibility to certain cancers.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

TRAF3 Interacting Protein 2 (TRAF3IP2)

host

Goat

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

recommended dilution

P-ELISA: 1/2000. Optimal dilutions/concentrations should be determined by the end user.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

TRAF3IP2

dry ice

availability

Shipped within 5-10 working days.

alias

Adapter protein CIKS,Connection to IKK and SAPK,JNK,E3 ubiquitin-protein ligase CIKS,CANDF8, CIKS, PSORS13

gene id

https://www.ncbi.nlm.nih.gov/gene/10758

NCBI accession

NP_679211.1, NP_001157753.1

note

Concentration: 0.5 mg/ml -

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