TNFRSF1A Associated Via Death Domain Protein (TRADD) Antibody
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935106861
info@markelab.com
Precio
221€ (50 µg)
Antibody anti-TRADD
proveedor
Abbexareference
abx326299Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Monkeystatus
RUOclonality
PolyclonalDescripción
TRADD Antibody is a Rabbit Polyclonal against TRADD.
Background
TNFRSF1A Associated Via Death Domain (TRADD) is an adaptor protein critical for tumor necrosis factor (TNF)-mediated signaling. It acts as a central platform for assembling signaling complexes upon TNF receptor 1 (TNFR1) activation. TRADD mediates divergent pathways leading to apoptosis, necroptosis, or NF-κB activation, depending on the recruited proteins. It plays a pivotal role in immune responses, inflammation, and cell death regulation. Aberrations in TRADD function are linked to immune dysregulation, chronic inflammation, and cancer. Its dual role in promoting cell survival and death makes it a crucial target for therapeutic strategies.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Monkey
immunogen target
TNFRSF1A Associated Via Death Domain Protein (TRADD)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
size 1
50 µg
size 2
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
TRADD
dry ice
No
availability
Shipped within 5-10 working days.
alias
NFRSF1A associated via death domain,TRADD
uniprot id
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