Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
442€ (200 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx274146
Tested Applications
WB, IHC, IF/ICC
Description
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Tissue Factor Pathway Inhibitor (TFPI).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tissue Factor Pathway Inhibitor (TFPI) |
| Host | Rabbit |
| Reactivity | Rat |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 4°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | EPI, LACI, TFI, TFPI1,Extrinsic pathway inhibitor,EPI |
| Background | Antibody anti-TFPI |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Tissue Factor Pathway Inhibitor (TFPI) is a crucial regulator of the extrinsic coagulation cascade, primarily inhibiting the tissue factor (TF)-factor VIIa complex and factor Xa to maintain hemostasis and prevent excessive thrombosis. It is a Kunitz-type serine protease inhibitor, produced mainly by endothelial cells, and circulates bound to lipoproteins or as a free plasma protein. TFPI acts as a feedback inhibitor that ensures balanced thrombin generation, thereby reducing the risk of pathological clot formation. Dysregulation or deficiency in TFPI has been linked to thrombotic disorders and cardiovascular diseases. Beyond its anticoagulant role, TFPI exhibits anti-inflammatory properties, reducing vascular inflammation and protecting against atherosclerosis. It is also involved in angiogenesis and endothelial cell function, making it significant in vascular biology.
Productos relacionados
Tissue Factor Pathway Inhibitor (TFPI) Antibody
TFPI Antibody is a Rabbit Polyclonal antibody against TFPI. This gene encodes a protease inhibitor that regulates the ti…
Ver producto
Mouse Tissue Factor Pathway Inhibitor (TFPI) ELISA Kit
Mouse Tissue Factor Pathway Inhibitor (TFPI) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mous…
Ver producto
Human Tissue Factor Pathway Inhibitor (TFPI) Protein
Human Tissue Factor Pathway Inhibitor (TFPI) protein is a recombinant protein expressed in E. coli.…
Ver producto