Thyroxine Binding Globulin / TBG (SERPINA7) Antibody
Pida mas información
935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-SERPINA7
proveedor
Abbexareference
abx032951Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
SERPINA7 is the major thyroid hormone transport protein in man (summarized by Mori et al., 1995 [PubMed 8530630]). Inherited abnormalities in the level of serum TBG have been classified as partial deficiency, complete deficiency, and excess. Patients are euthyroid.
Background
SERPINA7, also known as Thyroxine-Binding Globulin (TBG), is a glycoprotein primarily responsible for the transport of thyroid hormones in the bloodstream. It belongs to the serpin superfamily of proteins, which are typically serine protease inhibitors. However, like SERPINA6, SERPINA7 functions not as a protease inhibitor but as a carrier protein. The thyroid hormones, particularly thyroxine (T4) and to a lesser extent triiodothyronine (T3), are critical for regulating metabolism, growth, and development. SERPINA7 ensures that these hormones are delivered to tissues in a controlled and regulated manner.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Thyroxine Binding Globulin / TBG (SERPINA7)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
recommended dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINA7
dry ice
No
availability
Shipped within 5-10 working days.
alias
TBG,TBGQTL,T4-binding globulin,Serpin A7,Thyroxine-binding globulin
uniprot id
NCBI accession
NP_000345.2
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