Thyrotropin-Releasing Hormone Receptor (TRHR) Antibody (Biotin)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Thyrotropin-Releasing Hormone Receptor (TRHR) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx337974
Tested Applications
ELISA
Description
TRHR Antibody (Biotin) is a Rabbit Polyclonal against TRHR.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Thyrotropin-Releasing Hormone Receptor (TRHR) Immunogen: Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P34981 |
| Gene ID | 7201 |
| Alias | TRHR,TRH receptor,thyroliberin receptor,TRH-R,TRH-R1,CHNG7 |
| Background | Antibody anti-TRHR |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
The Thyrotropin-Releasing Hormone Receptor (TRHR) is a G protein-coupled receptor (GPCR) that is activated by thyrotropin-releasing hormone (TRH), a peptide hormone responsible for regulating the secretion of thyroid-stimulating hormone (TSH) from the pituitary gland. TRHR is primarily expressed in the anterior pituitary, where it plays a critical role in the regulation of thyroid function by stimulating the release of TSH. Upon activation, TRHR couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium levels, which in turn promotes the release of TSH and the synthesis of thyroid hormones (T3 and T4). TRHR also plays a role in regulating metabolic processes, growth, and development. Dysregulation of TRHR signaling is implicated in disorders such as hypothyroidism, hyperthyroidism, and thyroid tumors. Targeting TRHR with agonists or antagonists can be useful for managing thyroid-related conditions and regulating thyroid hormone production.
Productos relacionados
Thyrotropin-Releasing Hormone Receptor (TRHR) Antibody
Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and …
Ver producto Thyrotropin-Releasing Hormone Receptor (TRHR) Antibody
TRHR Antibody is a Rabbit Polyclonal against TRHR.…
Ver producto Thyrotropin-Releasing Hormone Receptor (TRHR) Antibody
TRHR Antibody is a Rabbit Polyclonal against TRHR.…
Ver producto