Thyroid Hormone Receptor Beta (THRB) Antibody

Este producto es parte de THR - thyroid hormone receptor
Product Graph
260€ (50 µg)

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935106861
info@markelab.com
name
Thyroid Hormone Receptor Beta (THRB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377588
tested applications
ELISA, WB, IHC

Description

Thyroid Hormone Receptor Beta (THRB) Antibody is a Rabbit polyclonal antibody for the detection of Human Thyroid Hormone Receptor Beta (THRB).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Thyroid Hormone Receptor Beta (THRB)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P10828
Gene ID
7068
NCBI Accession
NP_000452.2
Alias
TRb,GRTH,PRTH,THR1,ERBA2,NR1A2,THRB1,THRB2,Trbeta,THRbeta,TRbeta1,C-ERBA-2,THRbeta1,Thrbeta2,C-ERBA-BETA,Nuclear receptor subfamily 1 group A member 2
Background
Antibody anti-THRB
Status
RUO

Descripción

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Thyroid Hormone Receptor Beta (THRB) Antibody

THRB Antibody is a Rabbit Polyclonal antibody against THRB. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].

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