Thymidylate Synthase (TYMS) Antibody

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312€ (80 µl)

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935106861
info@markelab.com
name
Thymidylate Synthase (TYMS) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034613
tested applications
ELISA, WB, IHC, IF/ICC, FCM

Description

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Thymidylate Synthase (TYMS)
Immunogen: KLH-conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human TYSY.
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/2000, IHC-P: 1/500, IF/ICC: 1/50, FCM: 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 35.7 kDa
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC, FCM
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P04818
Background
Antibody anti-TYMS
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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