THO complex subunit 6 homolog (THOC6) Antibody (FITC)
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Description
THO complex subunit 6 homolog (THOC6) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human THOC6.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | THO complex subunit 6 homolog (THOC6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86W42 |
| Gene ID | 79228 |
| OMIM | 613680 |
| Background | Antibody anti-THOC6 |
| Status | RUO |
Descripción
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Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.
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