Thioredoxin Domain-Containing Protein 5 (TXNDC5) Antibody (Biotin)
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Description
EndoPDI Antibody is a Mouse Monoclonal against PDI.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Thioredoxin Domain-Containing Protein 5 (TXNDC5) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Biotin |
| Isotype | IgG2a |
| Purification | Purified by Protein G. |
| Size 1 | 100 µg |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NBS9 |
| Gene ID | 81567 |
| NCBI Accession | NP_001139021 |
| Background | Antibody anti-TXNDC5 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
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This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene.
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