Thioredoxin Domain-Containing Protein 5 (TXNDC5) Antibody
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Description
Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) Antibody is a Rabbit Polyclonal antibody against Thioredoxin Domain Containing 5 (Endoplasmic Reticulum).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Thioredoxin Domain-Containing Protein 5 (TXNDC5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NBS9 |
| Gene ID | 81567 |
| NCBI Accession | NP_001139021.1, NM_001145549.3, NP_110437.2, NM_030810.4 |
| OMIM | 616412 |
| Background | Antibody anti-TXNDC5 |
| Status | RUO |
Descripción
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This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
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This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene.
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