Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3) Antibody

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273€ (100 µg)

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935106861
info@markelab.com
name
Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx018082
tested applications
ELISA, WB

Description

PRDX3 Antibody is a Mouse Monoclonal antibody against PRDX3.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3)
Host
Mouse
Reactivity
Human
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Purification
Purified from ascites by Protein A chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NM_006793
Background
Antibody anti-PRDX3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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PRDX3 antibody

This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

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