CD63 Antigen (CD63) Antibody (FITC)
195€ (25 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
CD63 Antigen (CD63) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx414909
Tested Applications
FCM
Description
CD63 Antigen (CD63) Antibody (FITC) is a Mouse Monoclonal antibody against CD63 Antigen (CD63).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD63 Antigen (CD63) Immunogen: Rat |
| Host | Mouse |
| Reactivity | Rat |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Assay Type | Concentration: 0.1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 25 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28648 |
| Gene ID | 29186 |
| Alias | AD1,MLA1,ME491,HOP-26,OMA81H,Pltgp40,TSPAN30,Granulophysin,Lysosomal-associated membrane protein 3,Melanoma-associated antigen ME491 |
| Background | Antibody anti-CD63 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD63 molecule (CD63) is a transmembrane protein that belongs to the tetraspanin family, widely expressed in a variety of cell types and tissues. It plays a significant role in multiple biological processes, including immune response, cell adhesion, and intracellular trafficking. CD63 is prominently localized on late endosomes, lysosomes, and the plasma membrane, where it participates in the regulation of membrane fusion and vesicle trafficking. One of its most recognized roles is as a marker of exosomes, small extracellular vesicles released by cells, which makes it pivotal in cell-to-cell communication and a key target in exosome research for diagnostics and therapeutics. CD63 also interacts with integrins and other tetraspanins, facilitating cell adhesion and migration, processes that are critical in immune surveillance and tissue repair. It is involved in the activation of basophils and mast cells, contributing to allergic responses. Additionally, aberrations in CD63 expression or function are linked to pathological conditions, such as cancer metastasis, where it influences tumor cell invasiveness and immune evasion. Its expression has also been implicated in autoimmune diseases and infections. Given its multifunctional role and association with several diseases, CD63 continues to be an important molecule in immunological and biomedical research.
Productos relacionados
CD63 Antigen (CD63) Antibody
CD63 Antibody is a Rabbit Polyclonal Antibody against CD63.…
Ver producto
CD63 Antigen (CD63) Antibody (FITC)
CD63 Antibody (FITC) is a Mouse monoclonal antibody for human cds against CD63.…
Ver producto
CD63 Antigen (CD63) Antibody
CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cel…
Ver producto