CD63 Antigen (CD63) Antibody (APC)

Product specifications

Primary Antibodies

Target: CD63 Antigen (CD63)
Immunogen: abx069261 - Recombinant TSPAN30 (Ala103-Val203) expressed in E. coli

Rabbit

Human

Laser Line: 647
Excitation/Emission: 651/660

FCM: 9 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

APC

IgG

Purified by antigen-specific affinity chromatography.

100 tests

200 tests

500 tests

Liquid

FCM

Citrate-buffered saline, containing 0.02% NaN3, 50% glycerol.

Shipped within 5-15 working days.

Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light.

No

P08962

967

155740

AD1,MLA1,ME491,HOP-26,OMA81H,Pltgp40,TSPAN30,Granulophysin,Lysosomal-associated membrane protein 3,Melanoma-associated antigen ME491

Antibody anti-CD63

RUO

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

CD63 molecule (CD63) is a transmembrane protein that belongs to the tetraspanin family, widely expressed in a variety of cell types and tissues. It plays a significant role in multiple biological processes, including immune response, cell adhesion, and intracellular trafficking. CD63 is prominently localized on late endosomes, lysosomes, and the plasma membrane, where it participates in the regulation of membrane fusion and vesicle trafficking. One of its most recognized roles is as a marker of exosomes, small extracellular vesicles released by cells, which makes it pivotal in cell-to-cell communication and a key target in exosome research for diagnostics and therapeutics. CD63 also interacts with integrins and other tetraspanins, facilitating cell adhesion and migration, processes that are critical in immune surveillance and tissue repair. It is involved in the activation of basophils and mast cells, contributing to allergic responses. Additionally, aberrations in CD63 expression or function are linked to pathological conditions, such as cancer metastasis, where it influences tumor cell invasiveness and immune evasion. Its expression has also been implicated in autoimmune diseases and infections. Given its multifunctional role and association with several diseases, CD63 continues to be an important molecule in immunological and biomedical research.

Related Products

Human CD63 Antigen (CD63) Protein

Human Tetraspanin 30 (TSPAN30) is a recombinant Human protein expressed in E. coli.

Ver Producto