Testin (TES) Protein
234€ (2 µg)
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name
Testin (TES) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262857
tested applications
SDS-PAGE
Description
TES is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Testin (TES) |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q9UGI8 |
| Alias | TESS,TESS-2 |
| Background | Protein TES |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
TES is a tumor suppressor protein that belongs to the LIM domain-containing family, functioning in actin cytoskeletal organization, cell adhesion, and signaling regulation. TES interacts with focal adhesion proteins and actin-binding molecules to regulate cellular processes such as cell spreading, migration, and morphology. It acts as a scaffolding protein at focal adhesions, mediating interactions between the actin cytoskeleton and signaling molecules to maintain cell adhesion and structural integrity. TES is also involved in transcriptional regulation by interacting with nuclear proteins, including transcription factors, to control gene expression associated with cell growth and differentiation. Downregulation of TES is commonly observed in cancers, where its loss disrupts cytoskeletal organization and promotes tumor progression, metastasis, and reduced cell adhesion. Knockdown studies reveal increased cell motility, reduced cell adhesion, and enhanced invasive capacity, emphasizing TES’s critical role in maintaining cytoskeletal stability, suppressing tumor growth, and regulating cellular architecture.
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