Transcriptional Enhancer Factor TEF-4 (TEAD2) Antibody

Product Graph
377€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Transcriptional Enhancer Factor TEF-4 (TEAD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx238582
tested applications
ELISA, WB

Description

TEAD2 Antibody is a Rabbit Polyclonal against TEAD2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: TEA Domain Transcription Factor 2 (TEAD2)
Immunogen: TEA domain family member 2
Host
Rabbit
Reactivity
Human, Mouse
Assay Type
Concentration: 2 mg/ml
Recommended Dilution
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 55-65 kDa
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q15562
Gene ID
8463
OMIM
601729
Background
Antibody anti-TEAD2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

FNab08582

TEAD2 antibody

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds to the SPH and GT-IIC 'enhansons'(5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

Ver Producto
P9237

Recombinant Human TEAD2

Ver Producto
abx013624

Transcriptional Enhancer Factor TEF-4 (TEAD2) Antibody

Rabbit polyclonal antibody against TEAD2 protein. Immunogen region is Internal.

Ver Producto