TCRB Antibody
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Description
TCRB Antibody is a Mouse Monoclonal Antibody against TCRB.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TCRB |
| Host | Hamster |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 25 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Tested Applications | IHC, FCM, IP |
| Buffer | 0.2 µm filtered in PBS, pH7.2. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Do not freeze. |
| Dry Ice | No |
| Gene ID | 21577 |
| Background | Antibody anti-TCRB |
| Status | RUO |
Descripción
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T-Cell Receptor Beta Chain V Region CTL-L17 / TCRB (TRBV7-9) Antibody
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
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