Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Antibody
273€ (100 µl)
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Name
Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx103984
Tested Applications
WB, IHC
Description
Polyclonal Antibody to Acid Phosphatase 5, Tartrate Resistant (ACP5).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tartrate-Resistant Acid Phosphatase 5 / TRACP5 (ACP5) Immunogen: abx065095 - Recombinant ACP5 (Leu28-Gly286) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q05117 |
| Alias | HPAP,TRACP5a,TRACP5b,TRAP,TRAcP,TrATPase |
| Background | Antibody anti-ACP5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Acid phosphatases (ACP) are a group of enzymes that catalyze the hydrolysis of phosphate ester bonds under acidic conditions, resulting in the release of inorganic phosphate from organic molecules. These enzymes are characterized by their ability to function optimally at low pH levels. There are multiple forms of acid phosphatase, often denoted as ACP1, ACP2, ACP3, ACP4, and ACP5. Each isoform may have distinct tissue distribution, substrate specificity, and physiological roles. ACP1. It is found in various tissues and body fluids, including red blood cells, bone, prostate gland, and semen. It is a biomarker for poor prognosis in prostate cancer has been linked to bad clinical prognosis. ACP5 (Tartrate-Resistant Acid Phosphatase - TRAP) is mainly found in bone tissue, particularly in osteoclasts and Involved in bone resorption by osteoclasts, playing a critical role in bone remodeling and calcium homeostasis
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