T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody

Este producto es parte de CD80 molecule
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416€ (200 µl)

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935106861
info@markelab.com
name
T-lymphocyte activation antigen CD80 / B7-1 (CD80) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432481
tested applications
P-ELISA, WB, IHC, FCM

Description

CD80 Antibody is a Goat Polyclonal antibody against CD80.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
T-lymphocyte activation antigen CD80 / B7-1 (CD80)
Host
Goat
Reactivity
Human
Recommended Dilution
P-ELISA: 1/4000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB, IHC, FCM
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
941
NCBI Accession
NP_005182.1
Alias
B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80
Background
Antibody anti-CD80
Status
RUO
Note
Concentration: 0.5 mg/ml - 

Descripción

CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.

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