T-Cell Surface Glycoprotein CD4 (CD4) Antibody (FITC)
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Description
CD4 Antibody is a Mouse Monoclonal against CD4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Cell Surface Glycoprotein CD4 (CD4) |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | FCM: 1-4 μg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG2a Kappa |
| Clone ID | M469 |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P05540 |
| Gene ID | 24932 |
| Alias | T4,IMD79,Leu-3,OKT4D,CD4mut,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4 |
| Background | Antibody anti-CD4 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
The CD4 molecule is a glycoprotein expressed on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 plays a pivotal role in the immune system by aiding in the recognition of antigens and facilitating the immune response. It was identified as a critical component in the adaptive immune system, particularly in the context of T cell function and HIV infection, where it serves as a primary receptor for the virus.
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anti- CD4 antibody
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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