T-Cell Surface Glycoprotein CD4 (CD4) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
T-Cell Surface Glycoprotein CD4 (CD4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx028455
Tested Applications
ELISA, WB, FCM
Description
CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Cell Surface Glycoprotein CD4 (CD4) Immunogen: KLH-conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human CD4. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 51.1 kDa |
| Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01730 |
| NCBI Accession | NP_000607.1 |
| Alias | T4,IMD79,Leu-3,OKT4D,CD4mut,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4 |
| Background | Antibody anti-CD4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
The CD4 molecule is a glycoprotein expressed on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 plays a pivotal role in the immune system by aiding in the recognition of antigens and facilitating the immune response. It was identified as a critical component in the adaptive immune system, particularly in the context of T cell function and HIV infection, where it serves as a primary receptor for the virus.
Productos relacionados
T-Cell Surface Glycoprotein CD4 (CD4) Antibody
The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendrit…
Ver producto
T-Cell Surface Glycoprotein CD4 (CD4) Antibody
CD4 Antibody is a Rabbit Polyclonal antibody against Mouse and Rat.…
Ver producto