T-Cell Surface Glycoprotein CD4 (CD4) Antibody
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935106861
info@markelab.com
Precio
281.25€ (80 µl)
Antibody anti-CD4
proveedor
Abbexareference
abx028455Tested Applications
ELISA, WB, FCMreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Background
The CD4 molecule is a glycoprotein expressed on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 plays a pivotal role in the immune system by aiding in the recognition of antigens and facilitating the immune response. It was identified as a critical component in the adaptive immune system, particularly in the context of T cell function and HIV infection, where it serves as a primary receptor for the virus.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
T-Cell Surface Glycoprotein CD4 (CD4)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, FCM
purification
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CD4
dry ice
No
availability
Shipped within 5-10 working days.
alias
T4,IMD79,Leu-3,OKT4D,CD4mut,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4
uniprot id
NCBI accession
NP_000607.1
note
This product is for research use only.
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