T-Cell Surface Glycoprotein CD4 (CD4) Antibody
195€ (20 µl)
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935106861
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name
T-Cell Surface Glycoprotein CD4 (CD4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001304
tested applications
ELISA, WB, IF/ICC
Description
CD4 Antibody is a Rabbit Polyclonal antibody against CD4. This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Cell Surface Glycoprotein CD4 (CD4) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01730 |
| Gene ID | 920 |
| NCBI Accession | NP_000607.1 |
| Alias | T4,IMD79,Leu-3,OKT4D,CD4mut,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4 |
| Background | Antibody anti-CD4 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
The CD4 molecule is a glycoprotein expressed on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 plays a pivotal role in the immune system by aiding in the recognition of antigens and facilitating the immune response. It was identified as a critical component in the adaptive immune system, particularly in the context of T cell function and HIV infection, where it serves as a primary receptor for the virus.
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