T-Cell Differentiation Antigen CD6 (CD6) Antibody (FITC)
429€ (100 µg)
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935106861
info@markelab.com
name
T-Cell Differentiation Antigen CD6 (CD6) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx413477
tested applications
FCM
Description
T-Cell Differentiation Antigen CD6 (CD6) Antibody (FITC) is a Mouse Monoclonal antibody against T-Cell Differentiation Antigen CD6 (CD6).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | T-Cell Differentiation Antigen CD6 (CD6) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P30203 |
| Alias | TP120,T-cell differentiation antigen CD6,T12 |
| Background | Antibody anti-CD6 |
| Status | RUO |
| Note | Concentration: 0.1 mg/ml - |
Descripción
CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.
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