T-Cell Differentiation Antigen CD6 (CD6) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
T-Cell Differentiation Antigen CD6 (CD6) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx130028
Tested Applications
WB
Description
Cluster Of Differentiation 6 Antibody is a Rabbit Polyclonal against Cluster Of Differentiation 6.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Cell Differentiation Antigen CD6 (CD6) Immunogen: CD6 (Ser477-Pro644) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | TP120,T-cell differentiation antigen CD6,T12 |
| Background | Antibody anti-CD6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.
Productos relacionados
T-Cell Differentiation Antigen CD6 (CD6) Antibody
CD6 Antibody is a Rabbit Polyclonal Antibody against CD6.…
Ver producto
T-Cell Differentiation Antigen CD6 (CD6) Antibody
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded…
Ver producto
T-Cell Differentiation Antigen CD6 (CD6) Antibody
Rabbit polyclonal antibody against CD6 protein. Immunogen region is Internal.…
Ver producto