T-Cell Differentiation Antigen CD6 (CD6) Antibody

Product specifications

Primary Antibodies

T-Cell Differentiation Antigen CD6 (CD6)

Mouse

Pig

Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.

Monoclonal

Unconjugated

IgG2a

Purified

100 µg

Liquid

IHC, FCM

Contains sodium azide.

Shipped within 3-7 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

TP120,T-cell differentiation antigen CD6,T12

Antibody anti-CD6

RUO

Concentration: 1.0 mg/ml -

Descripción

CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.

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