Human Synaptotagmin 1 (SYT1) Protein
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Description
Human SYT1 is a recombinant protein expressed in E. coli.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Synaptotagmin 1 (SYT1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: 29.5 kDa Concentration: 0.25 mg/ml Sequence Fragment: 136-382 AA. Tag: C-terminal His-tag |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Purification | Purified by proprietary chromatographic techniques. |
| Size 1 | 1 µg |
| Size 2 | 5 µg |
| Size 3 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris-HCl, pH 8.0, containing 100 mM NaCl, 2 mM DTT and 20% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | For short-term storage, store at 4 °C for up to 4 weeks. For long-term storage, aliquot and store at -20 °C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21579 |
| Gene ID | 6857 |
| OMIM | 185605 |
| Background | Protein SYT1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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SYT1 antibody
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis(PMID: 8058779). SYT1(synaptotagmin I) was firstly identified as a 65-kDa protein with a wide distribution in neuronal and neurosecretory tissue(PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse(PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth(PMID: 15492212; 11078930; 10336114). This antibody recognizes endogenous SYT1, which has an experimentally determined molecular mass of 65-68 kDa. An additional band of 47 kDa could also be detected, which is corresponding to the calculated molecular weight of SYT1.
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