SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily E Member 1 (SMARCE1) Antibody

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Description
Rabbit Polyclonal against the SMARCE1 protein.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily E Member 1 (SMARCE1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by antigen affinity column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, WB |
Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q969G3 |
Gene ID | 6605 |
NCBI Accession | BC063700 |
OMIM | 603111 |
Background | Antibody anti-SMARCE1 |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
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SMARCE1 Antibody is a Rabbit Polyclonal antibody against SMARCE1. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
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