Sphingosine Kinase 2 (SPHK2) Antibody
442€ (120 µl)
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935106861
info@markelab.com
name
Sphingosine Kinase 2 (SPHK2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002301
tested applications
WB
Description
SPHK2 Antibody is a Rabbit Polyclonal antibody against SPHK2. This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Sphingosine Kinase 2 (SPHK2) Immunogen: Recombinant fusion protein corresponding to human SPHK2 |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 62 kDa/65 kDa/69 kDa/80 kDa Observed MW: 65 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 120 µl |
| Size 2 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NRA0 |
| Gene ID | 56848 |
| NCBI Accession | NP_001191088.1 |
| Background | Antibody anti-SPHK2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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SPHK2 antibody
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate(SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.
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