Sperm-Associated Antigen 8 (SPAG8) Antibody
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Description
SPAG8 Antibody is a Rabbit Polyclonal against SPAG8.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sperm-Associated Antigen 8 (SPAG8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/1000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99932 |
| Gene ID | 26206 |
| Background | Antibody anti-SPAG8 |
| Status | RUO |
Descripción
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SPAG8 antibody
Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau(By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida(By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis(PubMed:19548270). May play a role in fertility and microtubule formation through interaction with RANBP9(PubMed:10500252).
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Sperm Associated Antigen 8 (SPAG8) Antibody
Sperm Associated Antigen 8 Antibody is a Rabbit Polyclonal antibody against Sperm Associated Antigen 8.
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