Nesprin 2 (SYNE2) Antibody
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Description
Spectrin Repeat Containing Nuclear Envelope Protein 2 (SYNE2) Antibody is a Rabbit Polyclonal antibody against Spectrin Repeat Containing Nuclear Envelope Protein 2 (SYNE2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nesprin 2 (SYNE2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WXH0 |
| Gene ID | 23224 |
| Background | Antibody anti-SYNE2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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SYNE2 antibody
Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear(TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for centrosome migration to the apical cell surface during early ciliogenesis.
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Nesprin 2 (SYNE2) Antibody
Nesprin 2 Antibody is a Rabbit Polyclonal antibody against Nesprin 2.
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