Somatotropin / Growth Hormone (GH1) Antibody

286€ (100 µl)
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935106861
info@markelab.com
name
Somatotropin / Growth Hormone (GH1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104902
tested applications
WB, IHC, IF/ICC
Description
Somatotropin / Growth Hormone Antibody is a Rabbit Polyclonal against Somatotropin / Growth Hormone.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Somatotropin / Growth Hormone (GH1) |
Host | Rabbit |
Reactivity | Dog |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P33711 |
Gene ID | 403795 |
Alias | GH,GH-N,GHB5,GHN,IGHD1A,IGHD1B,IGHD2,hGH-N,Growth hormone 1,Pituitary growth hormone,HGH |
Background | Antibody anti-GH1 |
Status | RUO |
Note | Concentration: 0.71 mg/ml - |
Descripción
Growth hormone 1 (Somatotropin) (GH1) is a peptide hormone produced by the anterior pituitary gland that regulates growth, metabolism, and cellular regeneration GH1 plays a central role in stimulating growth during childhood and adolescence by promoting the proliferation and differentiation of chondrocytes in bone tissue, enhancing protein synthesis, and stimulating insulin-like growth factor-1 (IGF-1) production in the liver and peripheral tissues GH1 also regulates carbohydrate and lipid metabolism by enhancing lipolysis, increasing glucose availability, and influencing insulin sensitivity Dysregulation of GH1 production can lead to disorders such as gigantism and acromegaly (overproduction) or growth hormone deficiency, resulting in stunted growth and metabolic imbalances GH1 is also involved in muscle growth, tissue repair, and immune system regulation, highlighting its anabolic and regenerative roles GH1 levels decline with age, contributing to reduced muscle mass and increased fat accumulation, and its therapeutic administration is used to treat growth disorders and promote recovery in catabolic states Its wide-ranging effects on growth, metabolism, and tissue maintenance make GH1 a critical regulator of systemic physiology
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