Solute Carrier Family 44 Member 1 (SLC44A1) Antibody (PE)
429€ (100 tests)
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935106861
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name
Solute Carrier Family 44 Member 1 (SLC44A1) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx347178
tested applications
FCM
Description
Solute Carrier Family 44 Member 1 (SLC44A1) Antibody (PE) is a mouse monoclonal antibody against Solute Carrier Family 44 Member 1 (SLC44A1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Solute Carrier Family 44 Member 1 (SLC44A1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 μl/100 μl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 |
| Clone ID | K397 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q8WWI5 |
| Gene ID | 23446 |
| OMIM | 606105 |
| Alias | Choline transporter-like protein 1,CD92,CTL1,CDW92,CHTL1,CONATOC |
| Background | Antibody anti-SLC44A1 |
| Status | RUO |
Descripción
SLC44A1, also known as choline transporter-like protein 1 (CTL1), is a member of the solute carrier family involved in the transport of choline and other organic cations across cell membranes. SLC44A1 plays a crucial role in choline uptake, essential for the synthesis of phosphatidylcholine, a major phospholipid in cellular membranes, and acetylcholine, an important neurotransmitter in the nervous system. SLC44A1 is highly expressed in neuronal cells, kidney cells, and immune cells, reflecting its importance in neurotransmission, cellular membrane integrity, and metabolic regulation. Choline is essential in a variety of biological processes, including methylation reactions, membrane phospholipid synthesis, and acetylcholine production in cholinergic neurons. Deficiency in choline uptake, due to issues with SLC44A1 function, can lead to abnormalities in the nervous system and other health issues. In the brain, SLC44A1 is expressed in regions that are rich in cholinergic neurons, which underscores its importance in supporting neurotransmission. Moreover, SLC44A1 is implicated in mitochondrial function and is involved in phospholipid metabolism pathways, which affect cellular respiration and energy production.
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