Small Ubiquitin-Related Modifier 3 (SUMO3) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
Small Ubiquitin-Related Modifier 3 (SUMO3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025175
tested applications
ELISA, WB

Description

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Small Ubiquitin-Related Modifier 3 (SUMO3)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P55854
NCBI Accession
NP_008867.2
Background
Antibody anti-SUMO3
Status
RUO

Descripción

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Small Ubiquitin-Related Modifier 3 (SUMO3) Antibody

SUMO3 Antibody is a Rabbit Polyclonal antibody against SUMO3. This gene encodes a member of the small ubiquitin-related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants encoding distinct proteins have been described.

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