Small Ribosomal Subunit Protein Us15m (MRPS15) Antibody

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260€ (50 µg)

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935106861
info@markelab.com
name
Small Ribosomal Subunit Protein Us15m (MRPS15) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455737
tested applications
ELISA, WB, IHC

Description

Small Ribosomal Subunit Protein Us15m (MRPS15) Antibody is a Rabbit polyclonal antibody for the detection of Human Small Ribosomal Subunit Protein Us15m (MRPS15).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Small Ribosomal Subunit Protein Us15m (MRPS15)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P82914
Gene ID
64960
NCBI Accession
NP_112570.2
Background
Antibody anti-MRPS15
Status
RUO

Descripción

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.

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