Ras-Related Protein Rab-2A (RAB2A) Antibody
455€ (100 µl)
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Name
Ras-Related Protein Rab-2A (RAB2A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx159673
Tested Applications
ELISA, WB, IF/ICC
Description
RAB2A Antibody is a Mouse Monoclonal against RAB2A.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-2A (RAB2A) Immunogen: Recombinant fragment, corresponding to amino acids 39-206aa of human RAB2A (C-terminus). |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Dog, Pig |
| Recommended Dilution | WB: 1/500 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Antigen Affinity Purified |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61019 |
| Gene ID | 5862 |
| OMIM | 179509 |
| Alias | LHX,RAB2,Ras-related protein Rab-2A |
| Background | Antibody anti-RAB2A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB2A, member RAS oncogene family (RAB2A) is a small GTPase that is part of the RAS superfamily of proteins, which regulate intracellular vesicular trafficking and membrane dynamics RAB2A specifically plays a critical role in the transport of vesicles between the endoplasmic reticulum (ER) and the Golgi apparatus, an essential step in the secretory pathway that is crucial for protein sorting, glycosylation, and secretion Additionally, RAB2A is involved in regulating cell cycle progression, vesicular fusion, and cellular responses to stress Dysregulation of RAB2A can lead to various diseases, including cancer, where abnormal vesicular trafficking and cell proliferation are associated with tumor growth and metastasis Furthermore, alterations in RAB2A’s function are also implicated in neurodegenerative diseases, as defects in intracellular protein transport can disrupt cellular homeostasis and contribute to disease pathogenesis
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