SLP-76 Tyrosine Phosphoprotein Phospho-Tyr128 (LCP2 pY128) Cell ELISA Kit

Product Graph
546€ (192 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
SLP-76 Tyrosine Phosphoprotein Phospho-Tyr128 (LCP2 pY128) Cell ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx596075
tested applications
ELISA

Description

SLP-76 (pY128) Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
SLP-76 Tyrosine Phosphoprotein Phospho-Tyr128 (LCP2 pY128)
Reactivity
Human, Mouse, Rat
Detection Method
Fluorometric
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
192 tests
Tested Applications
ELISA
Availability
Shipped within 1-2 weeks.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q13094
Gene ID
3937
OMIM
601603
Background
Elisa Kits for: LCP2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Related Products

FNab07988

LCP2 antibody

Involved in T-cell antigen receptor mediated signaling.

Ver Producto
abx002004

Lymphocyte Cytosolic Protein 2 (LCP2) Antibody

LCP2 Antibody is a Rabbit Polyclonal antibody against LCP2. SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.

Ver Producto
abx067846

Mouse Lymphocyte Cytosolic Protein 2 (LCP2) Protein

Mouse Lymphocyte Cytosolic Protein 2 (LCP2) is a recombinant Mouse protein expressed in E. coli.

Ver Producto