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Sintilimab
Pida mas información
935106861
info@markelab.com
Precio
412.5€ (100 µg)
proveedor
Abbexareference
abx831496Tested Applications
ELISA, WBreactivity
Humanstatus
This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications (RUOclonality
MonoclonalDescripción
Sintilimab is a monoclonal antibody biosimilar expressed in CHO cells, targeting PDCD1/PD1/CD279, Sintilimab is a fully human anti-PD-1 antibody for tumor immunotherapy. It adopts IgG4 molecular framework and modified its hinge region sequence (S228P). Sintilimab, as a programmed death receptor 1 (PD-1) blocker, can bind to PD-1 molecules on the surface of T cells and relieve the inhibitory effect of PD-1 pathway on T cells.
Características del producto
category
Biosimilars
host
Human
clonality
Monoclonal
reactivity
Human
immunogen target
PDCD1/PD1/CD279
host
Human
isotype
IgG4 Kappa
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
size 1
100 µg
size 2
1 mg
expression
Recombinant
purity
> 95%
purification
Purified from cell culture supernatants by Protein A/G chromatography.
buffer
0.01 M PBS. pH 7.4.
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
dry ice
No
availability
Shipped within 7-12 working days.
alias
Biosimilars
note
CAS Number 2072873-06-2
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