Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5) Antibody

Este producto es parte de CD84 - CD84 molecule
Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5) Antibody
273€ (100 µl)

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Name
Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx104709
Tested Applications
WB

Description

Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5).

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Signaling Lymphocytic Activation Molecule Family, Member 5 (SLAMF5)
Immunogen: SLAMF5 (Ile43-Leu248)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
LY9B,Hcd84,mCD84,SLAMF5,SLAM family member 5,Cell surface antigen MAX.3,Hly9-beta,Leukocyte differentiation antigen CD84,Signaling lymphocytic activation molecule 5
Background
Antibody anti-CD84
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

CD84 is a surface glycoprotein that belongs to the Signaling Lymphocytic Activation Molecule (SLAM) family of receptors, which are part of the larger immunoglobulin superfamily (IgSF). It plays a significant role in the regulation of immune cell interactions, particularly in B and T lymphocytes, natural killer (NK) cells, and myeloid cells. CD84 is predominantly expressed in hematopoietic cells, where it mediates cell signaling processes related to immune regulation, cell adhesion, and inflammatory responses. CD84 is encoded by the CD84 gene, which is located on chromosome 1q23. It is widely expressed on immune cells such as B cells, T cells, dendritic cells, and monocytes, with notable expression also found on platelets. This molecule is critical for maintaining the balance of immune responses, including both activation and inhibition of immune functions. Due to its regulatory functions, CD84 has attracted considerable attention in immunology, cancer research, and autoimmune disease studies.

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