Signal Transducer and Activator of Transcription 4 (STAT4) Antibody

299€ (50 µl)
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935106861
info@markelab.com
name
Signal Transducer and Activator of Transcription 4 (STAT4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx402270
tested applications
ELISA, IHC, IF/ICC
Description
Signal Transducer and Activator of Transcription 4 (STAT4) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human STAT4.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Signal Transducer and Activator of Transcription 4 (STAT4) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Expression | Recombinant |
Purification | Purified by affinity chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC, IF/ICC |
Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q14765 |
OMIM | 180300 |
Background | Antibody anti-STAT4 |
Status | RUO |
Descripción
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STAT4 antibody
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
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