Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693) Antibody
208€ (20 µl)
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935106861
info@markelab.com
name
Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000189
tested applications
ELISA, WB, IHC
Description
STAT4 (pY693) Antibody is a Rabbit Polyclonal antibody against STAT4 (pY693). The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Data | Modification: Phosphorylation // Target Modification: Tyr693 |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14765 |
| Gene ID | 6775 |
| NCBI Accession | NP_003142.1 |
| Background | Antibody anti-STAT4 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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STAT4 antibody
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
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