Signal Regulatory Protein Gamma (SIRPG) Antibody (PE)
429€ (100 tests)
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935106861
info@markelab.com
name
Signal Regulatory Protein Gamma (SIRPG) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx347182
tested applications
FCM
Description
Signal Regulatory Protein Gamma (SIRPG) Antibody (PE) is a mouse monoclonal antibody against Signal Regulatory Protein Gamma (SIRPG).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Signal Regulatory Protein Gamma (SIRPG) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 μl/100 μl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 |
| Clone ID | D444 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q9P1W8 |
| Gene ID | 55423 |
| OMIM | 605466 |
| Alias | Signal-regulatory protein beta-2,CD172g,SIRPB2,SIRP-B2,bA77C3.1,SIRPgamma,CD172 antigen-like family member B |
| Background | Antibody anti-SIRPG |
| Status | RUO |
Descripción
Signal Regulatory Protein Gamma (SIRPG) is a member of the signal regulatory protein (SIRP) family, a subset of the immunoglobulin superfamily of cell-surface receptors. SIRPG is encoded by the SIRPG gene located on chromosome 20p13 in humans and is closely related to other family members such as SIRPA (SIRP alpha) and SIRPB (SIRP beta). This receptor plays an important role in immune cell signaling, particularly in immune regulation and cell-cell communication. SIRPG is primarily expressed on cells of the immune system, including T cells and dendritic cells, and plays a significant role in regulating cellular responses involved in immunity. Unlike SIRPA, which interacts with the CD47 ligand on other cells to inhibit macrophage phagocytosis and dendritic cell responses, SIRPG’s role centers on modulating T cell interactions, particularly in the context of immune responses and tissue homeostasis.
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