Signal Regulatory Protein Gamma (SIRPg) Antibody

Este producto es parte de SIRPG - signal regulatory protein gamma
Product Graph
741€ (1 ml)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Signal Regulatory Protein Gamma (SIRPg) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx174550
tested applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Signal Regulatory Protein Gamma (SIRPg)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Please enquire.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
Signal-regulatory protein beta-2,CD172g,SIRPB2,SIRP-B2,bA77C3.1,SIRPgamma,CD172 antigen-like family member B
Background
Antibody anti-SIRPG
Status
RUO

Descripción

Signal Regulatory Protein Gamma (SIRPG) is a member of the signal regulatory protein (SIRP) family, a subset of the immunoglobulin superfamily of cell-surface receptors. SIRPG is encoded by the SIRPG gene located on chromosome 20p13 in humans and is closely related to other family members such as SIRPA (SIRP alpha) and SIRPB (SIRP beta). This receptor plays an important role in immune cell signaling, particularly in immune regulation and cell-cell communication. SIRPG is primarily expressed on cells of the immune system, including T cells and dendritic cells, and plays a significant role in regulating cellular responses involved in immunity. Unlike SIRPA, which interacts with the CD47 ligand on other cells to inhibit macrophage phagocytosis and dendritic cell responses, SIRPG’s role centers on modulating T cell interactions, particularly in the context of immune responses and tissue homeostasis.

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