Signal-Regulatory Protein Gamma (SIRPG) Antibody
637€ (100 µl)
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Name
Signal-Regulatory Protein Gamma (SIRPG) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx115568
Tested Applications
ELISA, WB
Description
Signal-Regulatory Protein Gamma Antibody is a Rabbit Polyclonal antibody against Signal-Regulatory Protein Gamma.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Signal-Regulatory Protein Gamma (SIRPG) Immunogen: Human SIRPG. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P1W8 |
| Gene ID | 55423 |
| NCBI Accession | NP_001034597.1, NM_001039508.1, NP_061026.2, NM_018556.3 |
| OMIM | 605466 |
| Alias | Signal-regulatory protein beta-2,CD172g,SIRPB2,SIRP-B2,bA77C3.1,SIRPgamma,CD172 antigen-like family member B |
| Background | Antibody anti-SIRPG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Signal Regulatory Protein Gamma (SIRPG) is a member of the signal regulatory protein (SIRP) family, a subset of the immunoglobulin superfamily of cell-surface receptors. SIRPG is encoded by the SIRPG gene located on chromosome 20p13 in humans and is closely related to other family members such as SIRPA (SIRP alpha) and SIRPB (SIRP beta). This receptor plays an important role in immune cell signaling, particularly in immune regulation and cell-cell communication. SIRPG is primarily expressed on cells of the immune system, including T cells and dendritic cells, and plays a significant role in regulating cellular responses involved in immunity. Unlike SIRPA, which interacts with the CD47 ligand on other cells to inhibit macrophage phagocytosis and dendritic cell responses, SIRPG’s role centers on modulating T cell interactions, particularly in the context of immune responses and tissue homeostasis.
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