Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody (HRP)
Pida mas información
935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-SIGLEC7
proveedor
Abbexareference
abx316672Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
SIGLEC7 Antibody (HRP) is a Rabbit Polyclonal against SIGLEC7 conjugated to HRP.
Background
SIGLEC7, also known as p75/AIRM1, is an inhibitory receptor expressed on natural killer (NK) cells and some myeloid cells. It binds preferentially to α2-8-linked disialic acids found on both self and microbial surfaces, helping to suppress inappropriate immune activation. SIGLEC7 transmits inhibitory signals via immunoreceptor tyrosine-based inhibitory motifs (ITIMs), reducing NK cell-mediated cytotoxicity. This protein plays a critical role in maintaining self-tolerance and modulating responses to cancer and viral infections. It is frequently studied for its involvement in tumor immune evasion and as a target for immunotherapy.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7)
host
Rabbit
conjugation
HRP
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
SIGLEC7
dry ice
No
availability
Shipped within 5-10 working days.
alias
p75,QA79,AIRM1,CD328,AIRM-1,CDw328,D-siglec,SIGLEC-7,SIGLECP2,SIGLEC19P,p75/AIRM1,Adhesion inhibitory receptor molecule 1
uniprot id
NCBI accession
NP_001264130.1, NM_001277201.1, NP_055200.1, NM_014385.3
note
This product is for research use only.
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